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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAPK3
All Species:
28.79
Human Site:
S318
Identified Species:
57.58
UniProt:
O43293
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43293
NP_001339.1
454
52536
S318
S
S
L
P
P
N
N
S
Y
A
D
F
E
R
F
Chimpanzee
Pan troglodytes
XP_001140200
1430
160025
L318
L
I
S
L
C
Q
R
L
S
R
S
F
L
S
R
Rhesus Macaque
Macaca mulatta
XP_001101129
454
52535
S318
S
S
M
P
P
N
N
S
Y
A
N
F
E
R
F
Dog
Lupus familis
XP_533950
454
52750
T318
S
S
M
P
P
N
N
T
Y
V
N
F
E
R
F
Cat
Felis silvestris
Mouse
Mus musculus
O54784
448
51403
S313
S
S
M
P
R
N
T
S
Y
A
S
F
E
R
F
Rat
Rattus norvegicus
O88764
448
51431
S313
S
S
M
P
R
N
T
S
Y
A
S
F
E
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517613
524
60252
T388
S
S
M
P
P
N
N
T
Y
I
N
F
E
R
F
Chicken
Gallus gallus
NP_001026784
974
109076
L318
L
I
S
L
C
Q
R
L
S
R
S
F
L
S
R
Frog
Xenopus laevis
NP_001089464
452
52318
T318
S
S
M
P
P
N
N
T
Y
V
N
F
E
R
F
Zebra Danio
Brachydanio rerio
XP_690685
453
52525
T318
S
S
M
P
P
N
N
T
Y
I
N
F
E
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0KHT7
784
85666
Q360
Q
Q
Q
Q
Q
P
V
Q
Q
H
Q
L
A
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWL2
534
60474
E386
A
E
N
L
S
E
E
E
I
K
G
L
K
Q
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.9
98.9
95.3
N.A.
83.9
83.6
N.A.
76.1
34
78.1
80.4
N.A.
22.5
N.A.
N.A.
N.A.
Protein Similarity:
100
29.2
99.7
97.8
N.A.
90.9
90.7
N.A.
81.6
40.9
89.2
90.9
N.A.
35.4
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
73.3
N.A.
73.3
73.3
N.A.
73.3
6.6
73.3
73.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
93.3
N.A.
80
80
N.A.
93.3
6.6
93.3
93.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
34
0
0
9
0
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
9
9
0
0
0
0
67
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
67
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
9
17
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% K
% Leu:
17
0
9
25
0
0
0
17
0
0
0
17
17
0
0
% L
% Met:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
67
50
0
0
0
42
0
0
0
0
% N
% Pro:
0
0
0
67
50
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
9
9
9
17
0
9
9
0
9
0
0
9
0
% Q
% Arg:
0
0
0
0
17
0
17
0
0
17
0
0
0
67
17
% R
% Ser:
67
67
17
0
9
0
0
34
17
0
34
0
0
17
9
% S
% Thr:
0
0
0
0
0
0
17
34
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
9
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _